efficient and eco-friendly procedure for the synthesis of 2-amino-4h-chromenes catalyzed by diammonium hydrogen phosphate
Authors
abstract
an efficient and eco-friendly protocol for the preparation of 2-amino-4h-chromenes employing a multi-component, one-pot condensation reaction between aromatic aldehydes, malononitrile and1-naphthol has been developed. the reaction of 1-naphthol with malononitrile and various aromatic aldehydes was carried out in water-ethanol (1:1) at reflux using 20 mol% of diammonium hydrogen phosphate as catalyst. the results show that aromatic aldehydes containing electron-donating groups or electron-withdrawing groups could react smoothly to give the corresponding products in good to excellent yields. it was also found that diammonium hydrogen phosphate can be recycled at least four times without loss of activity. the operational simplicity, easy work-up, short reaction time, together with the use of non-toxic, commercially available, inexpensive and recyclable catalyst are remarkable features of the procedure.
similar resources
Efficient and Eco-Friendly Procedure for the Synthesis of 2-Amino-4H-Chromenes Catalyzed by Diammonium Hydrogen Phosphate
An efficient and eco-friendly protocol for the preparation of 2-amino-4H-chromenes employing a multi-component, one-pot condensation reaction between aromatic aldehydes, malononitrile and1-naphthol has been developed. The reaction of 1-naphthol with malononitrile and various aromatic aldehydes was carried out i...
full textOne-pot three component synthesis of 2-amino-4H-chromenes under green and high efficient conditions
A simple, mild and high efficient procedure for one pot three component synthesis of 2-amino 4-H chromene derivatives was studied. The reaction was performed in water using aryl aldehydes, malononitrile and resorcinol, phloroglucinol or naphthole in the presence of N-methyl D-glucamine (Meglumine) as a green high efficient catalyst. The reaction was studied in thermal, microwave (MW) and ultras...
full textOne-pot three component synthesis of 2-amino-4H-chromenes under green and high efficient conditions
A simple, mild and high efficient procedure for one pot three component synthesis of 2-amino 4-H chromene derivatives was studied. The reaction was performed in water using aryl aldehydes, malononitrile and resorcinol, phloroglucinol or naphthole in the presence of N-methyl D-glucamine (Meglumine) as a green high efficient catalyst. The reaction was studied in thermal, microwave (MW) and ultras...
full textEfficient and eco-friendly synthesis of quinoxalines derivatives catalyzed by acidic ionic liquids at room temperature
In this research, we have developed cheap recyclable and task-specific acidic ionic liquids (AILs) 1-hydrogen-3-methylimidazolium hydrogen sulfate [Hmim]HSO4, 1-hydrogen-3-methylimidazolium chloride [Hmim]Cl, 2-pyrrolidonium hydrogensulfate [Hnhp]HSO4 and applied them in acid catalyzed synthesis of quinoxaline derivatives from 1,2-phenylendiamines and 1,2-dicarbonyl compounds. The products coul...
full textEfficient and eco-friendly synthesis of quinoxalines derivatives catalyzed by acidic ionic liquids at room temperature
In this research, we have developed cheap recyclable and task-specific acidic ionic liquids (AILs) 1-hydrogen-3-methylimidazolium hydrogen sulfate [Hmim]HSO4, 1-hydrogen-3-methylimidazolium chloride [Hmim]Cl, 2-pyrrolidonium hydrogensulfate [Hnhp]HSO4 and applied them in acid catalyzed synthesis of quinoxaline derivatives from 1,2-phenylendiamines and 1,2-dicarbonyl compounds. The products coul...
full textA Simple and Green Procedure for the Synthesis of 5-Arylidenerhodanines Catalyzed by Diammonium Hydrogen Phosphate in Water
A simple and efficient procedure for the synthesis of 5-arylidenerhodanines by condensation of aromatic aldehydes with rhodanine in water using diammonium hydrogen phosphate as catalyst is described. The procedure offers several advantages including environmentally friendly, mild reaction conditions, short reaction times, high yields, and simple experimental and work-up procedures.
full textMy Resources
Save resource for easier access later
Journal title:
iranian journal of chemistry and chemical engineering (ijcce)Publisher: iranian institute of research and development in chemical industries (irdci)-acecr
ISSN 1021-9986
volume 34
issue 4 2015
Hosted on Doprax cloud platform doprax.com
copyright © 2015-2023